|
|
H2O + quercitrin <=> quercetin + L-rhamnose
|
3.2.1.40
alpha-L-rhamnosidase
3.2.1.66
quercitrinase
3.2.1.B28
3.2.1.B31
|
–
–
–
–
|
|
|
BRENDA:
BR16020;
BS423995
KEGG:
R02436
MetaCyc:
QUERCITRINASE-RXN
|
|
|
|
quercetin + O2 <=> 2-(3,4-dihydroxybenzoyloxy)-4,6-dihydroxybenzoate + CO
|
1.13.11.24
quercetin 2,3-dioxygenase
|
–
|
M
|
|
BRENDA:
BR40481
KEGG:
R02156
MetaCyc:
QUERCETIN-23-DIOXYGENASE-RXN
SABIO-RK:
2135
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> H+ + S-adenosyl-L-homocysteine + quercetin-3-O-methylether
|
2.1.1.104
caffeoyl-CoA O-methyltransferase
2.1.1.267
flavonoid 3',5'-methyltransferase
2.1.1.42
flavone 3'-O-methyltransferase
2.1.1.68
caffeate O-methyltransferase
2.1.1.76
quercetin 3-O-methyltransferase
2.1.1.B121
|
–
–
–
–
–
–
|
MK
|
|
BRENDA:
BR43918;
BS319718;
BS456599;
BS456600
KEGG:
R02157
MetaCyc:
QUERCETIN-3-O-METHYLTRANSFERASE-RXN;
RXN-8262
SABIO-RK:
14148;
2136
|
|
|
|
quercetin + 3''-phosphoadenylyl-sulfate <=> H+ + adenosine_3,5''-bisphosphate + quercetin_3-sulfate
|
2.8.2.25
flavonol 3-sulfotransferase
|
–
|
MK
|
|
BRENDA:
BR47987
KEGG:
R02159
MetaCyc:
FLAVONOL-3-SULFOTRANSFERASE-RXN
SABIO-RK:
2138
|
|
|
|
rutin + H2O <=> quercetin + rutinose + H+
|
3.2.1
3.2.1.B31
|
–
–
|
M
|
|
BRENDA:
BR50704
MetaCyc:
RXN-12530
|
|
|
|
quercetin_4''-O-glucoside + H2O <=> quercetin + D-glucose
|
3.2.1
3.2.1.21
beta-glucosidase
3.2.1.62
glycosylceramidase
|
–
–
–
|
M
|
|
BRENDA:
BS140026
MetaCyc:
RXN-13785
SABIO-RK:
12343;
12360
|
|
|
|
UDP-glucose + quercetin <=> quercetin-7-O-glucoside + UDP + H+
|
2.4.1.104
o-dihydroxycoumarin 7-O-glucosyltransferase
2.4.1.111
coniferyl-alcohol glucosyltransferase
2.4.1.170
isoflavone 7-O-glucosyltransferase
2.4.1.185
flavanone 7-O-beta-glucosyltransferase
2.4.1.237
flavonol 7-O-beta-glucosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.81
flavone 7-O-beta-glucosyltransferase
|
–
–
–
–
–
–
–
|
M
|
|
BRENDA:
BS321963;
BS445926
KEGG:
R06810
MetaCyc:
RXN-8264
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_3-O-glucoside + H+
|
2.4.1.115
anthocyanidin 3-O-glucosyltransferase
2.4.1.177
cinnamate beta-D-glucosyltransferase
2.4.1.35
phenol beta-glucosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
–
–
–
|
MK
|
|
BRENDA:
BS323087;
BS445961
KEGG:
R02158
MetaCyc:
RXN1F-462
SABIO-RK:
13061
|
|
|
|
UDP-galactose + quercetin <=> hyperoside + UDP + H+
|
2.4.1.234
kaempferol 3-O-galactosyltransferase
2.4.1.357
phlorizin synthase
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
–
–
|
M
|
|
BRENDA:
BS371203
MetaCyc:
RXN-14109
SABIO-RK:
14204
|
|
|
|
taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2 + H2O
|
1.14.20.4
anthocyanidin synthase
1.14.20.6
flavonol synthase
|
–
–
|
MK
|
|
BRENDA:
BS371257;
BS373099
KEGG:
R02160
MetaCyc:
RXN-527
SABIO-RK:
2139
|
|
|
|
quercetin_3-O-glucoside + H2O <=> quercetin + D-glucose
|
3.2.1
3.2.1.108
lactase
3.2.1.62
glycosylceramidase
3.2.1.B28
3.2.1.B31
|
–
–
–
–
–
|
M
|
|
BRENDA:
BS374513;
BS423698
MetaCyc:
RXN-13789
SABIO-RK:
12361
|
|
|
|
UDP-L-rhamnose + quercetin <=> quercitrin + UDP + H+
|
2.4.1
2.4.1.159
flavonol-3-O-glucoside L-rhamnosyltransferase
|
–
–
|
MK
|
|
BRENDA:
BS378173
KEGG:
R09803
MetaCyc:
RXN-8267
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> Rhamnetin + S-adenosyl-L-homocysteine
|
2.1.1
2.1.1.267
flavonoid 3',5'-methyltransferase
2.1.1.76
quercetin 3-O-methyltransferase
2.1.1.B75
2.1.1.B76
|
–
–
–
–
–
|
M
|
|
BRENDA:
BS419594;
BS456603
MetaCyc:
RXN-13906
|
|
|
|
kaempferol + reduced_flavodoxin + O2 <=> quercetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
1.14.14.82
flavonoid 3'-monooxygenase
|
–
–
|
K
|
|
BRENDA:
BS288546
KEGG:
R06538
|
|
|
|
quercetin_7-O-glucoside + H2O <=> quercetin + beta-D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
|
|
BRENDA:
BS371140
SABIO-RK:
12344
|
|
|
|
quercetin_3,4''-O-di-beta-D-glucopyranoside + H2O <=> quercetin + 2 beta-D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
|
|
BRENDA:
BS374512
SABIO-RK:
12353
|
|
|
|
quercetin + reduced_flavodoxin + O2 <=> myricetin + flavin + H2O
|
1.14.14.81
flavanoid 3',5'-hydroxylase
|
–
|
K
|
|
KEGG:
R10258
|
|
|
|
UDP-glucose + quercetin <=> quercetin_4''-O-glucoside + UDP + H+
|
2.4.1
|
–
|
M
|
|
MetaCyc:
RXN-10788
|
|
|
|
kaempferol + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14.82
flavonoid 3'-monooxygenase
|
–
|
M
|
|
MetaCyc:
RXN-12510
|
|
|
|
quercetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetagetin + oxidized_[NADPH-hemoprotein_reductase] + H2O
|
1.14.14
|
–
|
M
|
|
MetaCyc:
RXN-13898
|
|
|
|
quercetin + NADPH + O2 + H+ <=> gossypetin + NADP+ + H2O
|
1.14.99
|
–
|
M
|
|
MetaCyc:
RXN-15522
|
|
|
|
tamarixetin + reduced_[NADPH-hemoprotein_reductase] + O2 <=> quercetin + oxidized_[NADPH-hemoprotein_reductase] + formaldehyde + H2O + H+
|
1.14.14.1
unspecific monooxygenase
|
–
|
|
|
MetaCyc:
RXN66-589
|
|
|
|
dihydroquercetin + 2-oxoglutarate + O2 <=> quercetin + succinate + O2
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS397001
|
|
|
|
taxifolin + 2-oxoglutarate + O2 <=> quercetin + succinate + O2
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS375428
|
|
|
|
quercetin-4''-O-glucuronide + H2O <=> quercetin + D-glucuronate
|
3.2.1.31
beta-glucuronidase
|
–
|
|
|
BRENDA:
BS406542
|
|
|
|
Leucocyanidin + 2-oxoglutarate + O2 <=> quercetin + taxifolin + cyanidin + quercetin
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS375734
|
|
|
|
(2R,3S,4R)-leucocyanidin + 2-oxoglutarate + O2 <=> quercetin + taxifolin + cyanidin + quercetin
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS375733
|
|
|
|
dihydroquercetin + 2-oxoglutarate + O2 <=> quercetin + CO2 + H2O
|
1.14.20.6
flavonol synthase
|
–
|
|
|
BRENDA:
BS373098
|
|
|
|
(2R,3S,4R)-leucocyanidin + 2-oxoglutarate + O2 <=> taxifolin + cis-dihydroquercetin + quercetin + succinate + CO2
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS375430
|
|
|
|
Leucocyanidin + 2-oxoglutarate + O2 <=> quercetin + succinate + CO2
|
1.14.20.4
anthocyanidin synthase
|
–
|
|
|
BRENDA:
BS375431
|
|
|
|
quercetin-3-O-beta-D-glucuronide + H2O <=> quercetin + D-glucuronate
|
3.2.1.31
beta-glucuronidase
3.2.1.B44
|
–
–
|
|
|
BRENDA:
BS406541
|
|
|
|
quercetin_4''-O-beta-D-glucuronide + H2O <=> quercetin + beta-D-glucuronate
|
3.2.1.31
beta-glucuronidase
|
–
|
|
|
BRENDA:
BS452771
|
|
|
|
UDP-glucuronate + quercetin <=> UDP + quercetin_7-O-beta-D-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS402156
|
|
|
|
UDP-D-xylose + quercetin <=> UDP + quercetin_3-O-beta-D-xylose
|
2.4.1.91
flavonol 3-O-glucosyltransferase
2.4.2.56
kaempferol 3-O-xylosyltransferase
|
–
–
|
|
|
BRENDA:
BS390053
|
|
|
|
UDP-glucuronate + quercetin <=> UDP + quercetin_beta-D-glucuronoside
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS436058
|
|
|
|
quercetin + UDP-glucuronate <=> UDP + quercetin_O-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS322246
|
|
|
|
UDP-galactose + quercetin <=> UDP + 7-O-beta-D-galactosylquercetin
|
2.4.1.81
flavone 7-O-beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS456893
|
|
|
|
3 quercetin + 3 UDP-glucuronate <=> 3 UDP + quercetin_7-glucuronide + quercetin_3-glucuronide + quercetin_3''-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS454959
|
|
|
|
quercetin + UDP-glucuronate <=> UDP + quercetin_7-glucuronide + quercetin_4''-glucuronide_+quercetin_3''-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS456310
|
|
|
|
UDP-glucuronate + quercetin <=> UDP + quercetin_beta-D-glucuronide
|
2.4.1.17
glucuronosyltransferase
|
–
|
|
|
BRENDA:
BS378159
|
|
|
|
UDP-5-thio-glucose + quercetin <=> UDP + quercetin_3-O-5-thio-beta-D-glucoside
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS389943
|
|
|
|
UDP-mannose + quercetin <=> UDP + quercetin_3-O-beta-D-mannoside
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS390032
|
|
|
|
UDP-N-acetyl-D-glucosamine + quercetin <=> UDP + quercetin_3-O-N-acetylglucoside
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS390050
|
|
|
|
quercetin_7-O-beta-D-glucuronide + H2O <=> quercetin + D-glucuronate
|
3.2.1.31
beta-glucuronidase
|
–
|
|
|
BRENDA:
BS406543
|
|
|
|
quercetin-4''-glucoside + H2O <=> quercetin + D-glucose
|
3.2.1.108
lactase
3.2.1.62
glycosylceramidase
|
–
–
|
|
|
BRENDA:
BS374515
|
|
|
|
quercetin_3,4''-O-di-beta-D-glucopyranoside + 2 H2O <=> quercetin + 2 D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
|
|
BRENDA:
BS443870
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> S-adenosyl-L-homocysteine + 4''-methoxyquercetin
|
2.1.1.155
kaempferol 4'-O-methyltransferase
2.1.1.231
flavonoid 4'-O-methyltransferase
|
–
–
|
|
|
BRENDA:
BS374602
|
|
|
|
2 S-adenosyl-L-methionine + quercetin <=> 2 S-adenosyl-L-homocysteine + 3,7-O-dimethylquercetin
|
2.1.1.B75
2.1.1.B76
|
–
–
|
|
|
BRENDA:
BS419809
|
|
|
|
4 S-adenosyl-L-methionine + quercetin <=> 4 S-adenosyl-L-homocysteine + 3,3'',5,7-tetra-O-methyl-quercetin
|
2.1.1.42
flavone 3'-O-methyltransferase
|
–
|
|
|
BRENDA:
BS455025
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> S-adenosyl-L-homocysteine + 3,3'',5,7-tetramethoxyquercetin
|
2.1.1.267
flavonoid 3',5'-methyltransferase
2.1.1.76
quercetin 3-O-methyltransferase
|
–
–
|
|
|
BRENDA:
BS454630
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> S-adenosyl-L-homocysteine + 5-methoxyquercetin
|
2.1.1.267
flavonoid 3',5'-methyltransferase
2.1.1.76
quercetin 3-O-methyltransferase
|
–
–
|
|
|
BRENDA:
BS456601
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> S-adenosyl-L-homocysteine + patuletin
|
2.1.1.267
flavonoid 3',5'-methyltransferase
2.1.1.76
quercetin 3-O-methyltransferase
|
–
–
|
|
|
BRENDA:
BS456602
|
|
|
|
rutin + caffeic_acid <=> quercetin + caffeic_acid_3''-O-rutinoside
|
3.2.1.168
hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
|
–
|
|
|
BRENDA:
BS450562
|
|
|
|
rutin + ferulic_acid <=> quercetin + ferulic_acid_4''-O-rutinoside
|
3.2.1.168
hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
|
–
|
|
|
BRENDA:
BS450563
|
|
|
|
glutathione + 2''-(glutathione-S-yl)-quercetin <=> GSSG + quercetin
|
1.8.5.7
glutathionyl-hydroquinone reductase
|
–
|
|
|
BRENDA:
BS439576
|
|
|
|
S-adenosyl-L-methionine + quercetin <=> Rhamnetin
|
2.1.1.82
3-methylquercetin 7-O-methyltransferase
|
–
|
|
|
BRENDA:
BS421453
|
|
|
|
dTDP-glucose + quercetin <=> dTDP + quercetin_3-O-glucoside
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS388629
|
|
|
|
dTDP-xylose + quercetin <=> dTDP + quercetin_3-O-beta-D-xylose
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS388630
|
|
|
|
quercetin + GDP <=> diphosphate + guanosine_5''-pppAACAG
|
2.7.7.88
GDP polyribonucleotidyltransferase
|
–
|
|
|
BRENDA:
BS437829
|
|
|
|
GDP-glucose + quercetin <=> GDP + quercetin_3-O-glucoside
|
2.4.1.91
flavonol 3-O-glucosyltransferase
|
–
|
|
|
BRENDA:
BS388731
|
|
|
|
sucrose + quercetin <=> D-fructose + quercetin_3-O-glucoside
|
2.4.1.4
amylosucrase
|
–
|
|
|
BRENDA:
BS456781
|
|
|
|
sucrose + quercetin <=> D-fructose + quercetin_glucoside
|
2.4.1.373
alpha-(1->2) branching sucrase
|
–
|
|
|
BRENDA:
BS450706
|
|
|
|
quercetin-3-O-beta-D-glucopyranoside + H2O <=> quercetin + D-glucose
|
3.2.1.21
beta-glucosidase
|
–
|
|
|
BRENDA:
BS443871
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_7-O-glucoside + quercetin_3-O-glucoside
|
2.4.1.237
flavonol 7-O-beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS390014
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_3''-O-beta-D-glucoside + quercetin_7-O-glucoside + quercetin_7,3''-di-O-beta-D-glucoside
|
2.4.1.35
phenol beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS378054
|
|
|
|
UDP-glucose + quercetin <=> UDP + 7-O-beta-D-glucosylquercetin
|
2.4.1.81
flavone 7-O-beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS322995
|
|
|
|
UDP-glucose + quercetin <=> UDP + 4-O-beta-D-glucosyl-quercetin
|
2.4.1.126
hydroxycinnamate 4-beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS356098
|
|
|
|
UDP-glucose + quercetin <=> UDP + quercetin_7-O-glucoside + quercetin_4''-O-beta-D-glucoside
|
2.4.1.237
flavonol 7-O-beta-glucosyltransferase
|
–
|
|
|
BRENDA:
BS390015
|
|
|
|
3''-phosphoadenylyl_sulfate + quercetin <=> adenosine_3'',5''-bisphosphate + quercetin_3''-O-sulfate + quercetin_4''-O-sulfate
|
2.8.2.1
aryl sulfotransferase
|
–
|
|
|
BRENDA:
BS436823
|
|
|
|
3''-phosphoadenylylsulfate + quercetin <=> adenosine_3'',5''-bisphosphate + quercetin_sulfate
|
2.8.2.4
estrone sulfotransferase
|
–
|
|
|
BRENDA:
BS360498
|
|
|
|
adenosine_3''-phosphate_5''-phosphosulfate + quercetin <=> adenosine_3'',5''-bisphosphate + quercetin_7-sulfate
|
2.8.2.28
quercetin-3,3'-bissulfate 7-sulfotransferase
|
–
|
|
|
BRENDA:
BS387795
|
|
|
|
2S-adenosyl-L-methionine + quercetin <=> S-adenosyl-L-homocysteine + rhamnazin
|
2.1.1.82
3-methylquercetin 7-O-methyltransferase
|
–
|
|
|
BRENDA:
BS454948
|
|
|
|
4-nitrophenyl_sulfate + quercetin <=> 4-nitrophenol + quercetin_3''-O-sulfate
|
2.8.2.22
aryl-sulfate sulfotransferase
|
–
|
|
|
BRENDA:
BS436928
|
|
|
|
4-nitrophenyl_sulfate + quercetin <=> 4-nitrophenol + quercetin_4''-sulfate
|
2.8.2.1
aryl sulfotransferase
|
–
|
|
|
BRENDA:
BS436929
|
|
|
|
ATP + H2O + quercetin <=> ADP + phosphate + quercetin
|
7.6.2.2
ABC-type xenobiotic transporter
|
–
|
|
|
BRENDA:
BS445116
|
|
|
|
ADP-glucose + quercetin <=> ADP + quercetin_3-O-glucoside
|
2.4.1.357
phlorizin synthase
|
–
|
|
|
BRENDA:
BS444886
|
|
|
|
rutin + vanillic_acid <=> quercetin + vanillic_acid_4''-O-rutinoside
|
3.2.1.168
hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
|
–
|
|
|
BRENDA:
BS450565
|
|
|
|
rutin + Sinapic_acid <=> quercetin + sinapic_acid_4''-O-rutinoside
|
3.2.1.168
hesperidin 6-O-alpha-L-rhamnosyl-beta-D-glucosidase
|
–
|
|
|
BRENDA:
BS450564
|
|
|
|
quercetin-3-O-beta-D-glucopyranoside + H2O <=> quercetin + beta-D-glucose
|
3.2.1.62
glycosylceramidase
|
–
|
|
|
BRENDA:
BS140027
|
|
|
|
quercetin + H2O2 <=> oxidized_quercetin + H2O
|
1.11.2.2
myeloperoxidase
|
–
|
|
|
BRENDA:
BS406540
|
|